力学系セミナー:Building a Database of Dynamics for Regulatory Networks

開催日時
2015年   5月 26日 15時 00分 ~   16時 30分
場所
北海道大学理学部 3 号館 205 号室
講演者
Konstantin Mischaikow (Rutgers University)
 
講演タイトル:
Building a Database of Dynamics for Regulatory Networks

アブストラクト:
There are fundamental challenges to understanding the dynamics of regulatory networks, a problem is central to systems biology. Biological regulatory networks are typically nonlinear multiscale systems and hence that the associated mathematical models are often characterized by heuristic nonlinearities and poorly defined parameters. Even when the parameters are well defined, their values are typically unknown. Furthermore, precise experimental time series data for these systems is not available.

To deal with these issues we propose a novel mathematically rigorous but computable approach to nonlinear dynamics based on combinatorics and algebraic topology. We refer to the output of the computations as a Database of
Dynamics as it allows the user to query for specific dynamic structures. We will discuss the Database of Dynamics in the context of regulatory networks that are modeled using switching networks.

関連項目

研究集会・セミナー・集中講義の一覧へ